Publications
Here is a list of publications by year including primary research articles, reviews and book chapters.
List of Publications
2024
- Kujawska M, Neuhaus K, Huptas C, Jiménez E, Arboleya S, Schaubeck M, Hall LJ. Exploring the potential probiotic properties of Bifidobacterium breve DSM 32583 – a novel strain isolated from human milk. 2024. Probiotics and Antimicrobial Proteins.
- Dalby MJ, Kiu R, Serghiou IR, Miyazaki A, Acford-Palmer H, Tung R, Caim S, Phillips S, Kujawska M, Matsui M, Iwamoto A, Taking B, Cox SE, Hall LJ. Gut microbiota and faecal cytokine profiles of rural Cambodian infants and links to early life nutrition and diarrhoeal episodes. npj Biofilms and Microbiomes. 2024.
- Lopez-Tello J, Kiu R, Schofield Z, van Sinderen D, Le Gall G, Sferruzzi-Perri AN/Hall LJ. Maternal gut Bifidobacterium breve modifies fetal brain metabolism in germ-free mice. Molecular Metabolism. 2024.
- Mudhluli TE, Kujawska M, Mueller J, Felsl A, Truppel BA. Hall LJ, Chitsike I Gomo E, Zhou DT. Exploring the Genomic Traits of infant-associated Microbiota Members from a Zimbabwean Cohort. BMC Genomics. 2024. 25, 718.
- Gooch HCC, Labedan M, Hall LJ, Maxwell A. Transplanting human infant gut microbiome species into Galleria mellonella. BMC Research Notes. 2024.
- Camargo A, Rámirez JD, Kiu R, Hall LJ, Muñoz M. Unveiling the pathogenic mechanisms of Clostridium perfringens toxins and virulence factors. Emerging Microbes & Infections. 2024.
- Jain V/Dalby MJ, Alexander EC, Burford C, Gerasimidis K, Acford-Palmer H, Serghiou IR, Teng NMY, Kiu R, Zafeiropoulou K, Logan M, Verma A, Davenport M, Dhawan A/Hall LJ. Association of gut microbiota and gut metabolites and adverse outcomes in Biliary Atresia - a longitudinal prospective cohort controlled study. Hepatology Communications. 2024.
- Seki D, Kirkegaard R, Osvatic J, Hausmann B, Silva J, Pjevac P, Berger A, Hall LJ, Wisgrill L, Berry D. Gut microbiota genome features associated with brain injury in extremely premature infants. Gut Microbes. 2024.
2023
- Zhou DT, Mudhluli TE, Hall LJ, Manasa J, Munyati S. A scoping review of early-life gut microbiota and Bifidobacterium research in Zimbabwe: Implications for future studies. Pediatric Health, Medicine and Therapeutics. 14: 483-496 (2023)
- Kennedy KM, de Goffau MC, Perez-Muñoz ME, Arrieta MC, Bӓckhed F, Belkaid Y, Bork P, Braun T, Bushman FD, Dore J, de Vos WM, Earl AM, Eisen JA, Michal A. Elovitz, MD21, Ganal-Vonarburg SC, Gӓnzle MG, Garrett WS, Hall LJ, Hornef MW, Huttenhower C, Konnikova L, Lebeer S, Macpherson AJ, Massey RC, McHardy AC, Koren O, Lawley TD, Ley RE, O’Mahony L, O’Toole PW, Pamer EG, Parkhill J, Raes J, Rattei T, Salonen A, Segal E, Segata N, Shanahan F, Sloboda DM, Smith GCS, Sokol H, Spector TD, Surette MG, Tannock GW, Walker AW, Yassour M, Walter J. Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies. Nature 613: 639–649 (2023)
- Acuna-Gonzalez A, Kujawska M, Youssif M, Atkinson T, Grundy S, Hutchison A, Tremlett C, Clarke P/Hall LJ. Bifidobacterium bacteraemia is rare with routine probiotics use in preterm infants: a further case report with literature review. Anaerobe. (2023)
- James SA, Telatin A, Baker D, Evans R, Phillips S, Clarke P, Hall LJ, Carding SR. Draft Genome Sequence of a Preterm Infant-Derived Isolate of Candida parapsilosis. Microbiology Resource Announcements. (2023)
- Zenner C, Chalklen L, Adjei H, Dalby MJ, Mitra S, Cornwell E, Shaw A, Sim K, Kroll JS, Hall LJ. Non-invasive faecal cytokine and microbiome profiles predict commencement of necrotizing enterocolitis in a proof-of-concept study. Gastro Hep Advances. (2023)
- Neumann CJ, Mahnert A, Kumpitsch C, Kiu R, Dalby MJ, Kujawska M, Kurath-Koller S, Urlesberger B, Resch B, Hall LJ, Moissl-Eichinger C. Clinical NEC prevention practices drive different microbiome profiles and functional responses in the preterm intestine. Nature Communications. 14, 1349. (2023)
- Roager HM, Stanton C, Hall LJ. Microbial metabolites as modulators of the infant gut microbiome and host-microbial interactions in early life. Gut Microbes. (2023)
- Seki D, Errerd T, Hall LJ. The role of human milk fats in shaping neonatal development and the early life gut microbiota. Microbiome Research Reports. (2023)
- Kadia BM, Otiti MI, Ramsteijn AS, Sow D, Faye B, Heffernan C, Hall LJ, Webster JP, Walker AW, Allen S. Modulating the early life gut microbiota using pro-, pre- and synbiotics to improve gut health, child development and growth. Nutrition Reviews. (2023)
- Kiu R, Shaw A, Sim K, Acuna-Gonzalez A, Price C, Bedwell H, Dreger S, Fowler W, Cornwell E, Pickard D, Belteki G, Malsom J, Philips S, Young GR, Schofield Z, Alcon-Giner C, Berrington JE, Stewart C, Dougan G, Clarke P, Douce G, Robinson SD, Kroll JS, Hall LJ. Particular genomic and virulence traits are associated with preterm infant-derived toxigenic Clostridium perfringens strains. Nature Microbiology. (2023)
- Teng NMY, Kiu K, Evans R, Baker DJ, Zenner C, Robinson SD/Hall LJ. Allocoprobacillus halotolerans sp. nov and Coprobacter tertius isolated from human gut microbiota. IJSEM. (2023)
- Serghiou IR, Baker D, Evans R, Dalby M, Kiu R, Trampari E, Phillips S, Watt R, Atkinson T, Murphy B, Webber MA/Hall LJ. An efficient method for high molecular weight bacterial DNA extraction suitable for shotgun metagenomics from skin swabs. Microbial Genomics. (2023)
- Elek CKA, Brown TL, Le Viet T, Evans R, Baker DJ, Telatin A, Tiwari SK, Al-Khanaq H, Thilliez G, Kingsley RA, Hall LJ, Webber MA, Adriaenssens EM. A hybrid and poly-polish workflow for the complete and accurate assembly of phage genomes: a case study of ten przondoviruses. Microbial Genomics. (2023)
- Serghiou IR, Webber MA and Hall LJ. An update on the current understanding of the infant skin microbiome and research challenges. Current Opinion in Microbiology. (2023)
- Kujawska M, Schaubeck M, Hall LJ, Neuhaus K. Draft genome sequence of Bifidobacterium breve DSM 32583, isolated from human milk. Microbiology Resource Announcements. (2023)
- Saeed MH & Hall LJ. Early life antibiotic usage and impact on the gut microbiota, including emergence of antimicrobial resistant Enterococcus. Microbiota & Host. (2023)
2022
- Tran HNH, Thu TNH, Nguyen PH, Vo CN, Doan KV, Minh CNN, Nguyen NT, Ta VND, Vu KA, Hua TD, Nguyen TNT, Van TT, Duc TP, Duong BL, Hoang VC, Pham DT, Thwaites GE, Hall LJ, Slade DJ, Tran VH, Baker S, The HC. Tumour microbiomes and Fusobacterium genomics in Vietnamese colorectal cancer patients. NPJ Biofilms and Microbiomes (2022)
- Jordan A, Carding SR, Hall, LJ. The early life gut microbiome and vaccine efficacy. Lancet Microbe (2022)
- Clarke P, Card DJ, Nichols A, Ponnusamy V, Mahaveer A, Voong K, Dockery K, Holland N, Mulla S, Hall LJ, Maasen C, Lux P, Schurgers LJ, Harrington DJ, Shearer MJ. Exclusively breastfed preterm infants are at high risk of vitamin K insufficiency. Journal of Thrombosis and Haemostasis (2022)
- Hall LJ & Schirmer M. Editorial overview: current state and future of the microbiome field: why context matters. Current Opinion in Microbiology 70:102200 (2022)
- Hitch TCA, Hall LJ, Walsh SK, Leventhal G, Slack E, de Wouters T, Walter J, Clavel T. Microbiome-based interventions to modulate gut ecology and the immune system. Mucosal Immunology (2022)
- Lopez-Tello J/Schofield Z, Kiu R, Dalby MJ, van Sinderen D, Le Gall G, Sferruzzi-Perri AN/Hall LJ. Maternal microbiota Bifidobacterium promotes placental morphogenesis, nutrient transport and fetal growth in mice. Cellular and Molecular Life Science 79, 386 (2022)
- Brooks J, Modos D, Sudhakar P, Fazekas D, Zoufir A, Kapuy O, Szalay-Beko M, Madgwick M, Verstockt B, Hall LJ, Watson A, Tremelling M, Parkes M, Vermeire S, Bender A, Carding SR, Korcsmaros T. A systems genomics approach to uncover patient-specific pathogenic pathways and proteins in a complex disease. Nature Communications 13, 2299 (2022)
- Otiti MI, Kariuki S, Wang D, Hall LJ, Kuile FOT, Allen S. PRObiotics and SYNbiotics to improve gut health and growth in infants in western Kenya (PROSYNK Trial): Study protocol for a 4-arm, open-label, randomised, controlled trial. Trials (2022)
- Scott NA, Lawson MAE, Hodgetts RJ, Hall LJ, Mann ER. Macrophage metabolism in the intestine is compartment-specific and regulated by the microbiota. Immunology (2022)
- Kujawska M, Raulo A, Baltrūnaitė L, Knowles SCL, Hall LJ. Bifidobacterium castoris strains isolated from wild mice show evidence of frequent host switching and diverse carbohydrate metabolism potential. ISME Communications (2022)
2021
- Gooch HCC, Kiu R, Rudder S, Baker DJ, Maxwell A/Hall LJ. Enterococcus innesensis sp. nov., isolated from the wax moth Galleria mellonella. IJSEM (2021)
- Nikolova V, Smith M, Hall LJ, Cleare AJ, Stone JM and Young AH . Gut microbiota perturbations in psychiatric disorders: evidence for a trans-diagnostic pattern. An umbrella review. JAMA Psychiatry (2021).
- Chung The H, Ngoc Minh CN, Thi Hong CT, Thi Nguyen TN, Pike LJ, Zellmer C, Pham Duc T, Tran TA, Thanh TH, Van MP, Thwaites GE, Rabaa MA, Hall LJ, and Baker S. Exploring the genomic diversity and antimicrobial susceptibility of Bifidobacterium pseudocatenulatum in a Vietnamese population. MSystems (2021).
- Phillips S, Watt R, Atkinson T, Savva GM, Hayhoe A, Hall LJ. The Pregnancy and EARly Life study (PEARL) - A longitudinal study to understand how gut microbes contribute to maintaining health during pregnancy and early life. BMC Paediatrics. 21, 357 (2021).
- McKee AM/Kirkup BM, Madgwick M, Price CA, Dreger SA, Ansorge R, Makin KA, Caim S, Le Gall G, Paveley J, Leclaire C, Dalby MJ, Alcon-Giner C, Andrusaite A, Feng TY, Di Modica M, Triulzi T, Tagliabue E, Milling SWF, Weilbaecher KN, Rutkowski MR, Korcsmáros T, Robinson SD/Hall LJ. Antibiotic-induced disturbances of the gut microbiota result in accelerated breast tumour growth. iScience (2021).
- Shibu P, McCuaig F, McCartney AL, Kujawska M, Hall LJ, Hoyles L. The kleboxymycin biosynthetic gene cluster is encoded by several species belonging to the Klebsiella oxytoca complex. Microbial Genomics (2021).
- Henneke P, Kierdorf K, Hall LJ, Sperandio M, Hornef MW. Perinatal Development of Innate Immune Topology. eLife (2021).
- Dalby MJ & Hall LJ. Populating preterm infants with probiotics. Cell Reports Medicine 2 (3), 100224 (2021).
- Hall LJ & Robinson SD. Bacterial strains augment cancer therapeutics. Nature Microbiology 6: 275–276 (2021).
- Teng MYN, Price CA, McKee AM, Hall LJ, Robinson SD. Exploring the impact of gut microbiota and diet on Breast Cancer risk and progression. International Journal of Cancer (2021).
2020
- Osborne P, Hall LJ, Kronfeld-Schor N, Thybert D, Haerty W. A rather dry subject; investigating the study of arid-associated microbial communities. Environmental Microbiome (2020). 15 (1), 1-14
- James SA, Phillips S, Telatin A, Baker D, Ansorge R, Clarke P, Carding S/Hall LJ. Preterm Infants Harbour a Rapidly Changing Mycobiota That Includes Candida Pathobionts. Journal of Fungi. (2020) 6(4), 273
- Kujawska M, Collado MC, Hall LJ. Microbes, Human Milk, and Prebiotics In: Koren O and Rautava S (Eds). The Human Microbiome in Early Life: Implications to Health and Disease. San Diego: Elsevier Inc./Academic Press, 2021: 197-222.
- Alcon-Giner C, Dalby MJ, Caim S, Ketskemety J, Shaw A, Sim K, Lawson M, Kiu R, Leclaire C, Chalklen L, Kujawska M, Mitra D, Fardus-Reid F, Belteki, G, McColl K, Swann JR, Kroll JS, Clarke P, Hall LJ. Microbiota supplementation with Bifidobacterium and Lactobacillus modifies the preterm infant gut microbiota and metabolome: an observational study. Cell Reports Medicine (2020). doi: 10.1016/j.xcrm.2020.100077
- Kujawska M, Leanti La Rosa S, Pope PB, Hoyles L, McCartney AL, Hall LJ. Succession of Bifidobacterium longum strains in response to the changing early-life nutritional environment reveals specific adaptations to distinct dietary substrates. iScience (2020). doi: 10.1016/j.isci.2020.101368
- Kiu R, Treveil A, Harnisch LC, Caim S, Leclaire C, van Sinderen D, Korcsmaros T, Hall LJ. Bifidobacterium breve UCC2003 induces a distinct global transcriptomic programme in neonatal murine intestinal epithelial cells. iScience (2020). doi: 10.1016/j.isci.2020.101336
- Chen Y, Brook TC, Soe CZ, O’Neill I, Alcon-Giner C, Leelastwattanagul O, Phillips S, Caim S, Clarke P, Hoyles L/Hall LJ. Preterm infants harbour diverse Klebsiella populations, including atypical species that encode and produce an array of antimicrobial resistance- and virulence-associated factors. Microbial Genomics. (2020). doi:10.1099/mgen.0.000377
- Dalby MJ & Hall LJ. Recent advances in understanding the neonatal microbiome. F1000Research. (2020). doi:10.12688/f1000research.22355.1
- Wade LH & Hall LJ. Improving causality in microbiome research: can human genetic epidemiology help? Wellcome Open Research. (2020). doi:10.12688/wellcomeopenres.15628.3
- Puengel D, Treveil A, Dalby MJ, Caim S, Colquhoun IJ, Booth C, Ketskemety J, Korcsmaros T, van Sinderen D, Lawson MAE/Hall LJ. Bifidobacterium breve UCC2003 exopolysaccharide modulates the early life microbiota by acting as a potential dietary substrate. Nutrients. (2020). doi:10.3390/nu12040948
- Hughes KR/Schofield Z, Dalby MJ, Caim S, Chalklen L, Bernuzzi F, Alcon-Giner C, Le Gall G, Watson AJM, Hall LJ. The early life microbiota protects neonatal mice from pathological small intestinal epithelial cell shedding. FASEB. (2020). doi:10.1096/fj.202000042R
- Greenhough B, Read CJ, Lorimer J, Lezaun J, McLeod C, Benezra A, Bloomfield S, Brown T, D’Acquisto F, Clinch M, Dumitriu A, Evans J, Fawcett N, Fortané N, Hall LJ, Herrera CEG, Hodgetts T, Johnson KVA, Kirchhelle C, Krzywoszynska A, Lambert H, Monaghan T, Nading A, Nerlich B, Singer A, Szymanski E, and Wills J. Setting the agenda for social science research on the human microbiome. Palgrave Communications. (2020). doi:10.1057/s41599-020-0388-5
2019
- Alcon-Giner C/Leggett RM, Heavens D, Caim S, Brook TC, Kujawska M, Hoyles L, Clarke P, Clark MD/Hall LJ. Rapid MinION profiling of preterm microbiota and antimicrobial resistant pathogens. Nature Microbiology. (2019). doi:10.1038/s41564-019-0626-z
- Treveil A, Sudhakar P, Matthews ZJ, Wrzesinski T, Jones EJ, Brooks J, Olbei M, Hautefort I, Hall LJ, Carding SR, Mayer U, Powell PP, Wileman T, Di Palma F, Haerty W, Korcsmáros T. Identification of master regulators in goblet cells and Paneth cells using transcriptomics profiling of gut organoids and multi-layered networks. Molecular Omics. (2019). doi: 10.1039/c9mo00130a.
- Carruthers LV, Moses A, Adriko M, Faust CL, Tukahebwa EM, Ranford-Cartwright LC/Lamberton PHL/ Hall LJ. The impact of storage conditions on human stool 16S rRNA microbiome composition and diversity. PeerJ. (2019). doi:10.7717/peerj.8133
- Lawson MAE/O’Neill IJ, Kujawska M, Wijeyesekera A, Flegg Z, Chalklen L, Hall LJ. Breast-milk derived human milk oligosaccharides promote Bifidobacterium interactions within a single ecosystem. ISME J. (2019). doi:10.1038/s41396-019-0553-2
- Robertson, C., Savva, G.M., Clapuci, R., Jones, J., Maimouni, H., Brown, E., Minocha, A., Hall, L.J., Clarke, P. Incidence of necrotising enterocolitis before and after introducing routine prophylactic Lactobacillus and Bifidobacterium probiotics. Arch Dis Child Fetal Neonatal Ed. (2019). doi: 10.1136/archdischild-2019-317346
- McKee, A.M., Robinson, S.D. & Hall, L.J. The microbiota, antibiotics and breast cancer. Breast Cancer Management. (2019). doi: 10.2217/bmt-2019-0015
- Kiu, R., Brown, J., Bedwell, H., Leclaire, C., Caim, S., Pickard, D., Dougan, G., Dixon, R., Hall, L.J. Genomic analysis on broiler-associated Clostridium perfringens strains and caecal microbiome profiling reveals key factors linked to poultry Necrotic Enteritis. Animal Microbiome 1, 12. (2019). doi: 10.1186/s42523-019-0015-1
- Kiu, R., Caim, S., Painset, A., Pickard, D., Swift, C., Dougan, G., Mather, A. E., Amar, C., Hall L. J. Phylogenomic analysis of gastroenteritis-associated Clostridium perfringens in England and Wales over a 7-year period indicates distribution of clonal toxigenic strains in multiple outbreaks and extensive involvement of enterotoxin-encoding (CPE) plasmids. Microbial Genomics 297. (2019). doi: 10.1099/mgen.0.000297
- Kiu, R., Sim, K., Shaw, A., Cornwell, E., Pickard, D., Kroll, J. S., Hall, L. J. Genomic Analysis of Clostridium perfringens BEC/CPILE-Positive, Toxinotype D and E Strains Isolated from Healthy Children. Toxins 11, 543. (2019). doi: 10.3390/toxins11090543
- Chen, Y., Brook, T.C., Alcon, C., Clarke, P., Hall, L.J., Hoyles, L. Draft Genome Sequence of Raoultella ornithinolytica P079F W, Isolated from the Feces of a Preterm Infant. Microbiology resource announcements 8. (2019). doi: 10.1128/MRA.00493-19
- Chen, Y., Brook, T.C., Alcon, C., Clarke, P., Hall, L.J., Hoyles, L. Draft Genome Sequences of Citrobacter freundii and Citrobacter murliniae Strains Isolated from the Feces of Preterm Infants. Microbiology resource announcements 8. (2019). doi: 10.1128/MRA.00494-19
- Sultan, A., Mallen, C., Muller, S., Hider, S., Scott, I., Helliwell, T., Hall, L.J. Antibiotic use and the risk of rheumatoid arthritis: a population-based case-control study. BMC Medicine 17, 154. (2019). doi: 10.1186/s12916-019-1394-6
- Jones, E.J., Matthews, Z.J., Gul, L., Sudhakar, P., Treveil, A., Divekar, D., Buck, J., Wrzesinski, T., Jefferson, M., Armstrong, S.D., Hall, L.J., Watson, A.J.M., Carding, S.R., Haerty, W., Di Palma, F., Mayer, U., Powell, P.P., Hautefort, I., Wileman, T., and Korcsmaros, T. Integrative analysis of Paneth cell proteomic and transcriptomic data from intestinal organoids reveals functional processes dependent on autophagy. Dis Model Mech. (2019). doi: 10.1242/dmm.037069
- Rowe, W.P., Carrieri, A.P., Alcon-Giner, C., Caim, S., Shaw, A., Sim, K., Kroll, J.S., Hall, L.J., Pyzer-Knapp, E.O., and Winn, M.D. Streaming histogram sketching for rapid microbiome analytics. Microbiome 7, 40. (2019). doi: 10.1186/s40168-019-0653-2
2018
- Kiu, R. & Hall, L. J. An update on the human and animal enteric pathogen Clostridium perfringens. Emerging Microbes & Infections 7, 141, doi:10.1038/s41426-018-0144-8 (2018). doi: 10.1038/s41426-018-0144-8
- Scott, N.A., Andrusaite, A., Andersen, P., Lawson, M., Alcon-Giner, C., Leclaire, C., Caim, S., Le Gall, G., Shaw, T., Connolly, J.P.R., Roe, A.J., Wessel, H., Bravo-Blas, A., Thomson, C.A., Kastele, V., Wang, P., Peterson, D.A., Bancroft, A., Li, X., Grencis, R., Mowat, A.M., Hall, L.J., Travis, M.A., Milling, S.W.F., and Mann, E.R. Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis. Sci Transl Med 10. (2018). doi:10.1126/scitranslmed.aao4755
2017
- Kiu, R., Caim, S., Alexander, S., Pachori, P., Hall, L.J. Probing Genomic Aspects of the Multi-Host Pathogen Clostridium perfringens Reveals Significant Pangenome Diversity, and a Diverse Array of Virulence Factors. Front Microbiol 8, 2485. (2017). doi:10.3389/fmicb.2017.02485.
- O'Neill, I., Schofield, Z. & Hall, L. J. Exploring the role of the microbiota member Bifidobacterium in modulating immune-linked diseases. Emerging Topics in Life Sciences 1, 333-349. (2017). doi:10.1042/ETLS20170058
- Alcon-Giner, C., Caim, S., Mitra, S., Ketskemety, J., Wegmann, U., Wain, J., Belteki, G., Clarke, P., Hall, L.J. Optimisation of 16S rRNA gut microbiota profiling of extremely low birth weight infants. BMC Genomics 18,841 (2017). doi: 10.1186/s12864-017-4229-x
- Koskella, B., Hall, L.J., Metcalf, C.J.E. The microbiome beyond the horizon of ecological and evolutionary theory. Nature Ecology & Evolution 1, 11 (2017). doi: 10.1038/s41559-017-0340-2
- Kiu, R., Caim, S., Alcon-Giner, C., Belteki, G., Clarke, P., Pickard, D., Dougan, G., Hall, L.J. Preterm Infant-Associated Clostridium tertium, Clostridium cadaveris, and Clostridium paraputrificum Strains: Genomic and Evolutionary Insights. Genome Biology and Evolution 9,10. (2017). doi: 10.1093/gbe/evx210
- Hughes, K.R., Harnisch, L., Alcon-Giner, C., Mitra, S., Wright, C.J., Ketskemety, J., van Sinderen, D., Watson, A.J.M., Hall, L.J. Bifidobacterium breve reduces apoptotic epithelial cell shedding in an exopolysaccharide and MyD88-dependent manner. Open Biology. (2017). doi: 10.1098/rsob.160155
2015
2014
- Hall, L.J., Walshaw, J., Watson, A.J.M. Gut Microbiome in New-Onset Crohn’s Disease. Gastroenterology 147(4):932-934. (2014). doi: 10.1053/j.gastro.2014.08.014 show
- Forde, P., Sadadcharam, M., Hall, L.J., O’Donovan, T.R., de Kruijf, M., O' Sullivan, G., Soden, D. Enhancement of electroporation facilitated immunogene therapy via T-reg depletion. Cancer Gene Ther 21(8):349-54. (2014). doi: 10.1038/cgt.2014.35
- Forde, P., Hall, L.J., Sadadcharam, M., de Kruijf, M., O' Sullivan, G., Soden, D. Development and characterisation of an enhanced non viral expression vector (EEV) for electroporation cancer treatment. Mol. Ther. Methods Clin. Dev. 1, 14012. (2014). doi: 10.1038/mtm.2014.12
2013
- Williams, J.M., Duckworth, C.A., Watson, A.J.M., Frey, M.R., Miguel, J.C., Burkitt, M.D., Sutton, R., Hughes, K.R., Hall, L.J., Caamaño, J.H., Campbell, B.J., Pritchard, D.M. A mouse model of pathological small intestinal epithelial cell apoptosis and shedding induced by systemic administration of lipopolysaccharide. Dis. Model. Mech. 6(6):1388-99. (2013). doi: 10.1242/dmm.013284
- Hall, L.J., Murphy, C.T., Quinlan, A., Hurley, G., Shanahan, F., Nally, K., Melgar, S. Natural killer cells protect mice from DSS-induced colitis by regulating neutrophil function via the NKG2A receptor. Mucosal Immunol 6(5):1016-26. (2013). doi: 10.1038/mi.2012.140
- Watson, A.J.M. & Hall, L.J. Regulation of Host Gene Expression by Gut Microbiota. Gastroenterology. 144(4):841-844. (2013). doi: 10.1053/j.gastro.2013.02.028 show
- Hall, L.J., Murphy, C.T., Quinlan, A., Hurley, G., Shanahan, F., Nally, K., Melgar, S. Natural Killer cells protect against mucosal and systemic infection with the enteric pathogen Citrobacter rodentium. Infect Immun. 81(2):460-9. (2013). doi: 10.1128/IAI.00953-12
2012
- Watson AJM, Hall LJ, Hughes KR. Cell shedding: Old Questions Answered. Gastroenterology. 2012;143(5):1389-1391
- Hall LJ/Fanning S, van Sinderen D. Bifidobacterium breve UCC2003 surface-exopolysaccharide production is a beneficial trait mediating commensal-host interaction through immune modulation & pathogen protection. Gut Microbes. 2012;3(5):420-425
- Murphy CT, Hall LJ, Hurley G, Quinlan A, Shanahan F, Nally K, Melgar S. FTY720 Impairs Mucosal Immunity and Clearance of the Enteric Pathogen Citrobacter rodentium. Infect Immun. 2012;80(8):1032-1034
- Hall LJ & Watson AMJ. Role of Autophagy in NOD2-Induced Inflammation in Crohn’s Disease. Gastroenterology. 2012;142(4):1389-1391
- Hall LJ/Fanning S, Cronin M, Zomer A, MacSharry J, Goulding D, O’Connell-Motherway M, Shanahan F, Nally K, Dougan G, van Sinderen D. Bifidobacterial surface-exopolysaccharide facilitates commensal-host interaction through immune modulation & pathogen protection. Proc Natl Acad Sci U S A. 2012. 7;109(6):2108-13.
2011
- Hall LJ/ Jansen AM, , Clare S, Goulding D, Holt KE, Grant AJ, Mastroeni P, Dougan G, Kingsley RA. A Salmonella Typhimurium-Typhi genomic chimera: A murine-typhoid model to study Vi polysaccharide capsule function. PLoS Pathogens. 2011;7(7):e1002131.
- Dougan G, Goulding D, Hall LJ. Live Vaccines and their Role in Modern Vaccinology. Replicating Vaccines: A New Generation. Birkhauser Advances in Infectious Diseases. Springer (2011).
2010
- Hall LJ, Faivre E, Quinlan A, Shanahan F, Nally K, Melgar S. Induction and activation of adaptive immune populations during acute and chronic phases of a murine model of experimental colitis. Dig Dis Sci (2010) 56(1): 79-89.
- Murphy CT, Moloney G, Hall LJ, Quinlan A, Faivre E, Casey P, Shanahan F, Melgar S, Nally K. Use of bioluminescence imaging to track neutrophil migration and its inhibition in experimental colitis. Clin Exp Immunol (2010) 162(1): 188-96.
- Hall LJ, Clare S, Dougan G. Probing local innate immune responses after mucosal immunisation. J Immune Based Ther Vaccines (2010) 8:5.
- Hall LJ, Clare S, Dougan G. NK cells influence both innate and adaptive immune responses after mucosal immunization with antigen and mucosal adjuvant. J Immunol. (2010) 184(8):4327-37.
